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MacMODR has been a member of Linktree for 6 years and joined in May 2020. Resources MacMODR has populated their site with include: • Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice • MODR Trainee Seminar - March 6 2025 • MODR Seminar - Dr. Kacey Prentice - January 16, 2025 • 11th Annual MODR Symposium: Adipose tissue, Obesity & Vasular Disease • MODR Seminar – Dr. Christina Saed PDF Steinberg lab & Russta Fayyazi MSc (c) Steinberg lab • MODR Seminar - Dr. Shingo Kajimura - September 19 2024 • MODR seminar - March 21 2024 • MODR Seminar - March 7 2024 • MODR Seminar - February 15 2024 • MODR Seminar - February 1, 2024 • MODR Seminar - October 19, 2023 • MODR Seminar - October 5, 2023 • MODR Seminar – Graduate Student Presentations • MODR Seminar - Dr. Bryan Bergman, University of Colorado Anschutz Medical Campus • MODR Seminar – Dr. Ji-Young Lee, University of Connecticut • MODR Seminar – Dr. Daniel Moore, University of Toronto • MODR Seminar – Dr. Jean Phillipe Chaput, University of Ottawa • Promoting successful skeletal muscle repair: understanding a new “Twist” on muscle stem cells and the importance of having good neighbours • Deep learning of the retina enables the identification of novel causal biomarkers for microvascular health - Dr. Marie Pigeyre, McMaster University • Postdoctoral Fellow Position - Jeschke Lab • The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids • Vanier Scholars recognized for research excellence and potential • Mixed Lineage Kinase Domain-Like (MLKL) Protein: An Immunometabolic Nexus of Cardiovascular Disease - Dr. Adil Rashid, University of Ottawa • Burn induced hypermetabolism - some “burning” questions - Dr. Marc Jeschke, McMaster University • Environmental toxicants, brown adipose tissue, and potential links to obesity and metabolic disease • Zoom Registration MODR Seminar - November 3 2022 • Losing your nerve with ageing - Dr. Abigail Mackey, University of Copenhagen • Lessons in aging well for beginners: at the intersection of diet and physical activity - Dr. Stuart Phillips, McMaster University • High-fructose feeding suppresses cold-stimulated brown adipose tissue glucose uptake independently of changes in thermogenesis and the gut microbiome • 10th Annual Metabolism, Obesity and Diabetes Research Symposium • The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology • Screening and addressing social needs of children and families enrolled in a pediatric weight management program: a protocol for a pilot randomized controlled trial • Older persons with Type 1 diabetes face risk of reduced muscle strength and more cardiovascular issues, researchers find • Molecular mechanisms of muscle stem cell function and dysfunction - Dr. Natasha Chang - McGill University • Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia • Pediatrics' Tarnopolsky ranks among top medical scientists in Canada • Personalized Weight Management – is it time? Dr. Jill Hamilton - University of Toronto • Metabolic dysregulation and Alzheimer’s disease: can we slow the progression? - Rebecca Macpherson - Brock University • Metformin-induced reductions in tumor growth involves modulation of the gut microbiome • The effects of polycyclic aromatic compounds (PACs) on mammalian ovarian function • Prenatal nicotine exposure leads to decreased histone H3 lysine 9 (H3K9) methylation and increased p66shc expression in the neonatal pancreas • 2022 GradFlix Final Showcase • Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism • Effect of obesity treatment interventions in preschool children aged 2–6 years: a systematic review and meta-analysis • Aerobic exercise elicits clinical adaptations in myotonic dystrophy type 1 patients independent of pathophysiological changes • The effects of oil sands process-affected water naphthenic acid fraction components on GDF15 secretion in extravillous trophoblast cells • Growth and body composition trajectories in infants meeting the WHO growth standards study requirements • Updating the Canadian clinical practice guideline for managing pediatric obesity: a protocol • Skeletal Muscle Epigenetics with Exercise and Aging - Dr. Kevin Murach - University of Arkansas • High prevalence of PCOS in pediatric patients living with type 2 diabetes • Congratulations Robert Gutgesell • Scientists discover how caffeine protects against cardiovascular disease • Understanding insulin resistance in type 1 diabetes, and it’s relationship to cardiovascular disease. - Dr. Melanie Cree Green - University of Colorado Anschutz • Deriving Normative Data on 24-Hour Ambulatory Blood Pressure Monitoring for South Asian Children (ASHA): A Clinical Research Protocol • Mitochondrial turnover in muscle: Effects of exercise and age - Dr. David Hood - York University • Lipogenesis inhibitors: therapeutic opportunities & challenges • Heterogeneity of gestational diabetes: what can real world data on the OGTT tell us? Insights from Alberta - Dr. Rose Yeung - University of Alberta • A Novel Multi-Ingredient Supplement Activates a Browning Program in White Adipose Tissue and Mitigates Weight Gain in High-Fat Diet-Fed Mice • Extraneuronal manifestations in Spinal Muscular Atrophy - Dr. Rashmi Kothary - University of Ottawa • Disruption of autophagy by increased 5-HT alters gut microbiota and enhances susceptibility to experimental colitis and Crohn’s disease • Transitioning from basic research to a clinical laboratory analyst: A personal experience - Dr. Landry Nfonsam - Hamilton Regional Laboratory Program • World’s most cited researchers includes 18 from Faculty of Health Sciences • Medical Grand Rounds, November 18, 2021 • Experts still know surprisingly little about obesity’s origins • Job Posting – Postdoctoral Fellowship in Neighbourhood Effects and Child Health • Metabolic endotoxemia is dictated by the type of lipopolysacchacharides • Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota • McMaster's Centre for Metabolism, Obesity and Diabetes Research 2020 Annual Report • Individual and family characteristics associated with health indicators at entry into multidisciplinary pediatric weight management: findings from the CANadian Pediatric Weight management Registry (CANPWR) • Science Sketchbook - Sleep Hygiene • Combined metformin-salicylate treatment provides improved anti-tumor activity and enhanced radiotherapy response in prostate cancer; drug synergy at clinically relevant doses • The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue • GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease • $5 million awarded for child health research to explore effects of Covid and more • New research questions everything we know about our metabolism - CBC Here and Now Segment • Impaired Function and Altered Morphology in the Skeletal Muscles of Adult Men and Women With Type 1 Diabetes • "Infants’ First Solid Foods: Impact on Gut Microbiota Development in Two Intercontinental Cohorts • Moving beyond blood glucose with continuous multiplexed hormone measurement • Matrigel® enhances 3T3-L1 cell differentiation • Low dietary fiber promotes enteric expansion of a Crohn's disease-associated pathobiont independent of obesity • Vanier and Banting scholars recognized for their innovative research • Pai Lab • NT-proBNP versus routine clinical risk factors as a predictor of cardiovascular events or death in people with dysglycemia – A brief report from the ORIGIN trial • Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK • Timmons' Canada Research Chair (Tier 2) renewed • Assessing the Effect of Quality-Improvement Strategies for Organization of Care in Type 2 Diabetes Outcomes in Adults: Aim-Strait • Insulin Therapy: The Discovery That Shaped a Century • Metabolic-endocrine disruption due to preterm birth impacts growth, body composition, and neonatal outcome • Quarterly Highlights - April - June 2021 • Variability in How Canadian Pediatric Weight Management Clinics Deliver Care: Evidence from the CANadian Pediatric Weight Management Registry • Bacteria do not colonize the gut before birth, says collaborative study • U of Guelph researchers launch stress study amid pandemic, recruiting now for local families with young children • Prevalence of Hypertension and Albuminuria in Pediatric Type 2 Diabetes A Systematic Review and Meta-analysis • McMaster researcher probes ‘bogeyman’ protein behind diabetes-related cardiovascular illness • Investigating colonization patterns of the infant gut microbiome during the introduction of solid food and weaning from breastmilk: A cohort study protocol • Science Sketchbook - COVID-19: Creating a Healthy Routine at Home • Effectiveness of programs aimed at obesity prevention among Indigenous children: A systematic review • Perfecting the pitch: Trainees Zoom through 100+ studies during research fest • MODR Trainee Highlights • MODR Trainee Development Seminar • World Sleep Day 2021 • Spring forward: A fresh start on sleep habits • National Nutrition Month • Sevoflurane-induced hyperglycemia is attenuated by salsalate in obese insulin-resistant mice • Diabetes, Brain Infarcts, Cognition, and Small Vessels in the Canadian Alliance for Healthy Hearts and Minds Study • Inflammation promotes adipocyte lipolysis via IRE1 kinase • "Body mass index, waist circumference, waist-to-hip ratio, and body fat in relation to health care use in the Canadian Longitudinal Study on Aging" • WHO team in Wuhan tracks coronavirus origins as new variants rack up cases • Early Life Exposure to Nicotine: Postnatal Metabolic, Neurobehavioral and Respiratory Outcomes and the Development of Childhood Cancers • Obesity: Most kids don't choose what's for dinner • World’s most cited researchers includes 16 from Faculty of Health Sciences • Post‐transplant malignancies in pediatric organ transplant recipients • McMaster Centre for Metabolism, Obesity and Diabetes Research • Science Sketchbook • McMaster Centre for Metabolism, Obesity & Diabetes Research (MODR) Annual Report