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The NaPDI Center of Excellence conducts research on clinical relevance of NPDIs.
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NEED SUBJECTS - Kratom-Drug Interaction Study - Spokane, WA
NEED SUBJECTS - Kratom-Drug Interaction Study - Spokane, WA
Translating Kratom-Drug Interactions: From Bedside to Bench and Back
Translating Kratom-Drug Interactions: From Bedside to Bench and Back
Challenges in Pharmacovigilance: Variability in the Criteria for Determining Drug Associated Acute Kidney Injury (D-AKI) in Retrospective, Observational Studies
Challenges in Pharmacovigilance: Variability in the Criteria for Determining Drug Associated Acute Kidney Injury (D-AKI) in Retrospective, Observational Studies
Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries
Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries
Impact of drug-mediated inhibition of intestinal transporters
Impact of drug-mediated inhibition of intestinal transporters
Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice
Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice
Assessment of Orally Administered Δ9-THC When Coadministered With CBD
Assessment of Orally Administered Δ9-THC When Coadministered With CBD
Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom
Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom
Developing a Knowledge Graph for Pharmacokinetic NPDIs
Developing a Knowledge Graph for Pharmacokinetic NPDIs
Pharmacokinetic natural product-drug interactions (NPDIs) occur when botanical or other natural products are co-consumed with pharmaceutical drugs. Wi…
Limitations of fexofenadine limited sampling strategy using plasma concentrations
Limitations of fexofenadine limited sampling strategy using plasma concentrations
An evaluation of adverse drug reactions and outcomes attributed to kratom
An evaluation of adverse drug reactions and outcomes attributed to kratom
A Physiologically-Based Pharmacokinetic Model for Cannabidiol
A Physiologically-Based Pharmacokinetic Model for Cannabidiol
Broadening the capture of NPs mentioned in FAERS
Broadening the capture of NPs mentioned in FAERS
FDA issues another kratom warning following death
FDA issues another kratom warning following death
Coleus (Coleus forskholii) Coleus stem extract Nuclear Receptor Induction study - Ole Miss studies
Coleus (Coleus forskholii) Coleus stem extract Nuclear Receptor Induction study - Ole Miss studies
Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) studies
Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) studies
Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) studies
Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) studies
Goldenseal (Hydrastis canadensis) R21 Goldenseal Project Studies
Goldenseal (Hydrastis canadensis) R21 Goldenseal Project Studies
UNCG Honored for its Inclusive 'Chemistry' - UNC Greensboro
UNCG Honored for its Inclusive 'Chemistry' - UNC Greensboro
Seeking healthy subjects for a botanical-drug interaction study
Seeking healthy subjects for a botanical-drug interaction study
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective
Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach
Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach
Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products
Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products
A Case of Potential Pharmacokinetic Kratom-drug... : Journal of Addiction Medicine
A Case of Potential Pharmacokinetic Kratom-drug... : Journal of Addiction Medicine
Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes
Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes
Assessment of Orally Administered Δ9-THC When Coadministered With CBD
Assessment of Orally Administered Δ9-THC When Coadministered With CBD
Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom - PubMed
Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom - PubMed
Developing a Knowledge Graph for Pharmacokinetic Natural Product-Drug Interactions
Developing a Knowledge Graph for Pharmacokinetic Natural Product-Drug Interactions
Limitations of fexofenadine limited sampling strategy using plasma concentrations and partial area under the concentration-time curve to estimate transporter activity in healthy adults - PubMed
Limitations of fexofenadine limited sampling strategy using plasma concentrations and partial area under the concentration-time curve to estimate transporter activity in healthy adults - PubMed
An evaluation of adverse drug reactions and outcomes attributed to kratom in the US Food and Drug Administration Adverse Event Reporting System from January 2004 through September 2021
An evaluation of adverse drug reactions and outcomes attributed to kratom in the US Food and Drug Administration Adverse Event Reporting System from January 2004 through September 2021
Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2
Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2
A Physiologically-Based Pharmacokinetic Model for Cannabidiol in Healthy Adults, Hepatically-Impaired Adults, and Children
A Physiologically-Based Pharmacokinetic Model for Cannabidiol in Healthy Adults, Hepatically-Impaired Adults, and Children
650: Dr. Nicholas Oberlies: Finding Compounds in Fungi to Develop New Drugs to Fight Cancer - People Behind the Science Podcast
650: Dr. Nicholas Oberlies: Finding Compounds in Fungi to Develop New Drugs to Fight Cancer - People Behind the Science Podcast
Hierarchical cluster analysis of technical replicates to identify interferents in untargeted mass spectrometry metabolomics
Hierarchical cluster analysis of technical replicates to identify interferents in untargeted mass spectrometry metabolomics
2022-2023 Gateway Research Awar
2022-2023 Gateway Research Awar
Winners of the 2020 JA Ōmura Awards for excellence - The Journal of Antibiotics
Winners of the 2020 JA Ōmura Awards for excellence - The Journal of Antibiotics
Fabulous fungi and pharmacognosy with Dr. Nicholas Oberlies
Fabulous fungi and pharmacognosy with Dr. Nicholas Oberlies
Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach
Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach
Capturing the Complex Interplay Between Drugs and the Intestinal Microbiome
Capturing the Complex Interplay Between Drugs and the Intestinal Microbiome
Effects of Common CYP1A2 Genotypes and Other Key Factors on Intraindividual Variation in the Caffeine Metabolic Ratio: An Exploratory Analysis
Effects of Common CYP1A2 Genotypes and Other Key Factors on Intraindividual Variation in the Caffeine Metabolic Ratio: An Exploratory Analysis
Quantifying Hepatic Enzyme Kinetics of (-)-∆9-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC, through In Vitro Modeling
Quantifying Hepatic Enzyme Kinetics of (-)-∆9-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC, through In Vitro Modeling
Assessing Transporter-Mediated Natural Product-Drug Interactions Via In vitro-In Vivo Extrapolation
Assessing Transporter-Mediated Natural Product-Drug Interactions Via In vitro-In Vivo Extrapolation
Certain foods and beverages can interact with drugs
Certain foods and beverages can interact with drugs
Chemical composition and biological effects of kratom
Chemical composition and biological effects of kratom
Thummel and Paine share thoughts on the importance of mentorship through DMDD
Thummel and Paine share thoughts on the importance of mentorship through DMDD
Herbal Remedies | Chimikos Consulting | Nicholas H. Oberlies
Herbal Remedies | Chimikos Consulting | Nicholas H. Oberlies
Center of Excellence for Natural Product-Drug Interaction Research (NaPDI)
Center of Excellence for Natural Product-Drug Interaction Research (NaPDI)
Oberlies Research Group | UNCG
Oberlies Research Group | UNCG
Paine Research Group | WSU Pharmacy
Paine Research Group | WSU Pharmacy
Cech Research Group | UNCG
Cech Research Group | UNCG
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