@napdicenter

NEED SUBJECTS - Kratom-Drug Interaction Study - Spokane, WA

Translating Kratom-Drug Interactions: From Bedside to Bench and Back

Challenges in Pharmacovigilance: Variability in the Criteria for Determining Drug Associated Acute Kidney Injury (D-AKI) in Retrospective, Observational Studies

Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries

Impact of drug-mediated inhibition of intestinal transporters

Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice

Assessment of Orally Administered Δ9-THC When Coadministered With CBD

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom

Developing a Knowledge Graph for Pharmacokinetic NPDIs

Limitations of fexofenadine limited sampling strategy using plasma concentrations

An evaluation of adverse drug reactions and outcomes attributed to kratom

A Physiologically-Based Pharmacokinetic Model for Cannabidiol

Broadening the capture of NPs mentioned in FAERS

FDA issues another kratom warning following death

Coleus (Coleus forskholii) Coleus stem extract Nuclear Receptor Induction study - Ole Miss studies

Cat's-claw (Uncaria tomentosa) Identification of PXR activators from Uncaria tomentosa (Cat’s Claw) studies

Gou Teng (Uncaria rhynchophylla) Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) studies

Goldenseal (Hydrastis canadensis) R21 Goldenseal Project Studies

UNCG Honored for its Inclusive 'Chemistry' - UNC Greensboro

Seeking healthy subjects for a botanical-drug interaction study

Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective

Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants

Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach

Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products

A Case of Potential Pharmacokinetic Kratom-drug... : Journal of Addiction Medicine

Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes

Assessment of Orally Administered Δ9-THC When Coadministered With CBD

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom - PubMed

Developing a Knowledge Graph for Pharmacokinetic Natural Product-Drug Interactions

Limitations of fexofenadine limited sampling strategy using plasma concentrations and partial area under the concentration-time curve to estimate transporter activity in healthy adults - PubMed

An evaluation of adverse drug reactions and outcomes attributed to kratom in the US Food and Drug Administration Adverse Event Reporting System from January 2004 through September 2021

Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2

A Physiologically-Based Pharmacokinetic Model for Cannabidiol in Healthy Adults, Hepatically-Impaired Adults, and Children

650: Dr. Nicholas Oberlies: Finding Compounds in Fungi to Develop New Drugs to Fight Cancer - People Behind the Science Podcast

Hierarchical cluster analysis of technical replicates to identify interferents in untargeted mass spectrometry metabolomics

2022-2023 Gateway Research Awar

Winners of the 2020 JA Ōmura Awards for excellence - The Journal of Antibiotics

Fabulous fungi and pharmacognosy with Dr. Nicholas Oberlies

Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach

Capturing the Complex Interplay Between Drugs and the Intestinal Microbiome

Effects of Common CYP1A2 Genotypes and Other Key Factors on Intraindividual Variation in the Caffeine Metabolic Ratio: An Exploratory Analysis

Quantifying Hepatic Enzyme Kinetics of (-)-∆9-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC, through In Vitro Modeling

Assessing Transporter-Mediated Natural Product-Drug Interactions Via In vitro-In Vivo Extrapolation

Certain foods and beverages can interact with drugs

Chemical composition and biological effects of kratom

Thummel and Paine share thoughts on the importance of mentorship through DMDD

Herbal Remedies | Chimikos Consulting | Nicholas H. Oberlies

Center of Excellence for Natural Product-Drug Interaction Research (NaPDI)

Oberlies Research Group | UNCG

Paine Research Group | WSU Pharmacy

Cech Research Group | UNCG