drugdiscovery

drugdiscovery has been a member of Linktree for 9 months and joined in September 2025. Besides social media accounts, drugdiscovery has populated their site with Full article: SaeR as a novel target for antivirulence therapy against Staphylococcus aureus, Identification of a Small Molecule Compound Active against Antibiotic-Tolerant Staphylococcus aureus by Boosting ATP Synthesis, Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 | Nature, Differential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells | Microbiology Society, Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle | Journal of Virology, Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target | Science Advances, A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 | Nature Communications, Characterisation of Staphylococcus aureus virulence factor EsxA and structure-based screening of EsxA inhibitors for combating methicillin-resistant S aureus: abridged secondary publication | HKMJ, SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target | Nature Communications, Talaromyces marneffei Mp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts | Infection and Immunity, Suppression of Staphylococcus aureus virulence by a small-molecule compound | PNAS, Identification and characterization of GLDC as host susceptibility gene to severe influenza | EMBO Molecular Medicine, Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells - Journal of Biological Chemistry, Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response - ScienceDirect, www.sciencedirect.com, Metabolomic Profiling of Plasma from Melioidosis Patients Using UHPLC-QTOF MS Reveals Novel Biomarkers for Diagnosis, Identification of Novel Fusion Inhibitors of Influenza A Virus by Chemical Genetics | Journal of Virology, Lipid metabolites as potential diagnostic and prognostic biomarkers for acute community acquired pneumonia - ScienceDirect, Lipid mediators of inflammation as novel plasma biomarkers to identify patients with bacteremia - ScienceDirect, www.sciencedirect.com, NMR-based metabolomic urinalysis: A rapid screening test for urinary tract infection - ScienceDirect, Phosphatidic acid phosphatase 1 impairs SARS-CoV-2 replication by affecting the glycerophospholipid metabolism pathway, Broad‐spectrum antiviral activity of Spatholobus suberectus Dunn against SARS‐CoV‐2, SARS‐CoV‐1, H5N1, and other enveloped viruses - PMC, RSC - Page load error, SARS-CoV-2 exploits host DGAT and ADRP for efficient replication | Cell Discovery, Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction - ScienceDirect, Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication, SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target | Nature Communications, Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells, Suppression of Staphylococcus aureus virulence by a small-molecule compound | PNAS, Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats - ScienceDirect, In Silico Structure-Based Screening of Large Ligand Library Against Virulence Factors of Drug Resistant Pathogens, Home | CVVT.